Breakthrough Prize 2019: Winners

Recipients

1. Angelika Amon

   Biology

   for determining the consequences of aneuploidy, an abnormal chromosome number resulting from chromosome mis-segregation.

2. C. Frank Bennett

   Biology

   for the development of an effective antisense oligonucleotide therapy for children with the neurodegenerative disease spinal muscular atrophy.

3. Xiaowei Zhuang

   Biology

   for discovering hidden structures in cells by developing super-resolution imaging – a method that transcends the fundamental spatial resolution limit of light microscopy.

4. Zhijian Chen

   Biology

   for elucidating how DNA triggers immune and autoimmune responses from the interior of a cell through the discovery of the DNA-sensing enzyme cGAS.