Breakthrough Prize 2013: Winners

Recipients

1. Bert Vogelstein

   Biology

   for cancer genomics and tumor suppressor genes.

2. Charles Sawyers

   Biology

   for cancer genes and targeted therapy.

3. Cornelia Bargmann

   Biology

   for the genetics of neural circuits and behavior, and synaptic guidepost molecules.

4. David Botstein

   Biology

   for linkage mapping of Mendelian disease in humans using DNA polymorphisms.

5. Eric S. Lander

   Biology

   for the discovery of general principles for identifying human disease genes, and enabling their application to medicine through the creation and analysis of genetic, physical and sequence maps of the human genome.

6. Hans Clevers

   Biology

   for describing the role of Wnt signaling in tissue stem cells and cancer.

7. Lewis C. Cantley

   Biology

   for the discovery of PI 3-Kinase and its role in cancer metabolism.

8. Napoleone Ferrara

   Biology

   for discoveries in the mechanisms of angiogenesis that led to therapies for cancer and eye diseases.

9. Robert A. Weinberg

   Biology

   for characterization of human cancer genes.

10. Shinya Yamanaka

    Biology

    for induced pluripotent stem cells.

11. Titia de Lange

    Biology

    for research on telomeres, illuminating how they protect chromosome ends and their role in genome instability in cancer.