Breakthrough Prize 2013: Winners

Recipients

1. Fundamental Physics

   Alexander Polyakov

   Physics

   For his many discoveries in field theory and string theory including the conformal bootstrap, magnetic monopoles, instantons, confinement/de-confinement, the quantization of strings in non-critical dimensions, gauge/string duality and many others. His ideas have dominated the scene in these fields during the past decades.

2. Life Sciences

   Bert Vogelstein

   Biology

   for cancer genomics and tumor suppressor genes.

3. Life Sciences

   Charles Sawyers

   Biology

   for cancer genes and targeted therapy.

4. Life Sciences

   Cornelia Bargmann

   Biology

   for the genetics of neural circuits and behavior, and synaptic guidepost molecules.

5. Life Sciences

   David Botstein

   Biology

   for linkage mapping of Mendelian disease in humans using DNA polymorphisms.

6. Life Sciences

   Eric S. Lander

   Biology

   for the discovery of general principles for identifying human disease genes, and enabling their application to medicine through the creation and analysis of genetic, physical and sequence maps of the human genome.

7. Life Sciences

   Hans Clevers

   Biology

   for describing the role of Wnt signaling in tissue stem cells and cancer.

8. Life Sciences

   Lewis C. Cantley

   Biology

   for the discovery of PI 3-Kinase and its role in cancer metabolism.

9. Life Sciences

   Napoleone Ferrara

   Biology

   for discoveries in the mechanisms of angiogenesis that led to therapies for cancer and eye diseases.

10. Life Sciences

    Robert A. Weinberg

    Biology

    for characterization of human cancer genes.

11. Life Sciences

    Shinya Yamanaka

    Biology

    for induced pluripotent stem cells.

12. Life Sciences

    Titia de Lange

    Biology

    for research on telomeres, illuminating how they protect chromosome ends and their role in genome instability in cancer.