Stuart H. Orkin

賞

1. 2022

   カナダ・ガードナー国際賞

   生物学

   For the discovery of the molecular mechanism responsible for the switch from fetal to adult hemoglobin gene expression during human development and translating that knowledge into a novel treatment for the hemoglobin disorders – sickle cell disease and beta- thalassemia.

2. 2024

   ショウ賞 — 生命科学と医学

   生物学

   For their discovery of the genetic and molecular mechanisms underlying the fetal-to-adult hemoglobin switch, making possible a revolutionary and highly effective genome-editing therapy for sickle cell anemia and β thalassemia, devastating blood diseases that affect millions of people worldwide.

3. 2026

   ブレークスルー賞 — ライフサイエンス

   生物学

   For elucidating the mechanism driving the switch from fetal to adult hemoglobin and validating it as a therapeutic target for sickle-cell disease and beta-thalassemia.