Destinataire
Oliver Smithies
1925–2017 · Royaume-Uni · Mâle
Prix
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1990
Prix international Canada Gairdner
BiologieFor the discovery, development and application of gel electrophoresis methods that allow the separation and identification of specific proteins and nucleic acids.
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1993
Prix international Canada Gairdner
BiologieFor pioneering work in the use of homologous recombination to generate targeted mutations in the mouse.
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2001
Prix Lasker — Prix Albert Lasker pour la recherche médicale fondamentale
BiologieFor the development of a powerful technology for manipulating the mouse genome with exquisite precision, which allows the creation of animal models of human disease.
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2002/2003
Prix Wolf — Médecine
Biologiefor the development of procedures to manipulate mouse ova and embryos, which has enabled transgenesis and its applications in mice.
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2007
prix Nobel — Médecine
Biologiefor their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells