Premio Breakthrough · Ciencias de la vida
Premio Breakthrough 2014: Ganadores
Destinatarios
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Alexander Varshavsky
for discovering critical molecular determinants and biological functions of intracellular protein degradation.
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James P. Allison
for the discovery of T cell checkpoint blockade as effective cancer therapy.
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Mahlon DeLong
for defining the interlocking circuits in the brain that malfunction in Parkinson's disease – this scientific foundation underlies the circuit-based treatment of Parkinson's disease by deep brain stimulation.
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Michael N. Hall
for the discovery of Target of Rapamycin (TOR) and its role in cell growth control.
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Richard P. Lifton
for the discovery of genes and biochemical mechanisms that cause hypertension.
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Robert S. Langer
for discoveries leading to the development of controlled drug-release systems and new biomaterials.