Canada Gairdner International Award 2025: Winners

Recipients

1. Gary Struhl, Iva Greenwald, Spyros Artavanis-Tsakonas

   Biology

   For pioneering work on the Notch signalling pathway, which has significantly contributed to our understanding of how cells communicate with each other during development, how these signals regulate cell fate determination and how disruption can lead to developmental defects and cancer.

2. Michael J. Welsh, Paul Negulescu

   Biology

   For pioneering research into the cellular and molecular mechanisms underlying the genetic disease cystic fibrosis, leading to the development of transformative drug therapies based on these mechanisms, thereby improving and saving countless lives.