Canada Gairdner International Award 2007: Winners

Recipients

1. C. David Allis

   Biology

   For his transforming studies demonstrating the link between chromatin structure and gene transcription and elucidating the mechanisms by which a variety of post-translational modifications of histones are involved in gene expression and genome maintenance and stability.

2. Dennis J. Slamon

   Biology

   For the development of targeted therapy Herceptin against advanced breast cancer expressing the Her-2/Neu oncogene resulting in more effective therapy for breast cancer.

3. Harry F. Noller, Thomas A. Steitz

   Biology

   For his studies on the structure and function of the ribosome which showed that the peptidyl transferase was an RNA catalyzed reaction, and for revealing the mechanism of inhibition of this function by antibiotics.

4. Kim Nasmyth

   Biology

   For his discovery of the mechanism of chromosome segregation during cell division, which has profound implications for our understanding of chromosome non-disjunction in human cancer and other genetic diseases.