Breakthrough Prize

Breakthrough Prize 2025: Winners

Recipients

  1. Fundamental Physics

    ATLAS collaboration, CMS collaboration, ALICE collaboration, LHCb collaboration

    Physics

    For detailed measurements of Higgs boson properties confirming the symmetry-breaking mechanism of mass generation, the discovery of new strongly interacting particles, the study of rare processes and matter-antimatter asymmetry, and the exploration of nature at the shortest distances and most extreme conditions at CERN’s Large Hadron Collider.

  2. Life Sciences

    Daniel J. Drucker

    Biology

    For the discovery and characterization of GLP-1 and revealing its physiology and potential in treating diabetes and obesity.

  3. Life Sciences

    David R. Liu

    Biology

    For developing base editing and prime editing, technologies that edit the DNA of living systems without cutting the DNA double helix, and rewrite segments of genes at their native locations, enabling the correction or replacement of virtually any mutation.

  4. Life Sciences

    Stephen L. Hauser

    Biology

    For establishing the role of B cells in multiple sclerosis and developing B-cell based treatments, and for revealing that Epstein-Barr virus infection is the leading risk for multiple sclerosis.

  5. Mathematics

    Dennis Gaitsgory

    Math

    for his central role in the proof of the geometric Langlands conjecture.