カナダ・ガードナー国際賞 1969: 勝者

受賞者

1. Belding H. Scribner

   生物学

   For the concept of chronic intermittent hemodialysis; the arteriovenous cannulas which made it possible; his role in the development of "home" dialysis and continued basic and clinical investigation in his field. Chronic intermittent hemodialysis has prolonged the useful lives of thousands of patients throughout the world and has made renal transplantation feasible.

2. Earl Wilbur Sutherland

   生物学

   In recognition of his outstanding contributions to our understanding of the central role the adenylcyclase system plays in mediating many of the effects of hormones on metabolic processes.These discoveries, which emanated from a careful, imaginative and thorough analysis of the mechanisms by which epinephrine and glucagon increased glycogenolysis, have opened new fields for exploration.

3. Ernest McCulloch, James Till

   生物学

   In recognition of their development of the spleen colony technique for measuring the capacity of primitive normal and neoplastic cells to multiply and differentiate in the body. This technique has been applied by them and their colleagues, and by many others, to gain important knowledge of the normal formation of blood cells, the behaviour of leukemic cells and methods of treating leukemia, and other aspects of cell biology.

4. F. Mason Sones

   生物学

   In recognition of his outstanding contributions to the investigation and treatment of coronary artery disease and, in particular, for his introduction of the technique of selected coronary arteriography which has permitted radiographic visualization of individual obstruction as an objective criterion of the need for revascularization of the myocardium.

5. Frank J. Dixon

   生物学

   In recognition of his outstanding contributions in immunology and immunopathology, particularly his investigations dealing with the elucidation of the pathogenesis of serum sickness and of experimental and human glomerulonephritis.

6. John P. Merrill

   生物学

   In recognition of his contribution to the field of nephrology and particularly his pioneer work in kidney transplantation which has led to its development as a practical form of treatment and has advanced our knowledge of immunologic mechanisms.

7. Robert B. Salter

   生物学

   In recognition of his scientific contributions to an understanding of cartilage degeneration, epiphyseal necrosis, torsional deformation of bone and dysplasia of joints in relation to numerous musculoskeletal disorders, especially congenital dislocation of the hip. On the basis of his research he has designed safer treatment for young children and an original operation - innominate osteotomy - for older children both of which represent major advances in the prevention of degenerative arthritis of the hip in adult life.