Prix international Canada Gairdner 1968 : lauréats

Destinataires

1. Bruce Chown

   Biologie

   For his valuable contributions to the knowledge of human blood groups and particularly for his work on the diagnosis, treatment and prevention of hemolytic disease of the new­born, and for his leadership and inspiration of investigators concerned with clinical immunohematology.

2. George H. Hitchings

   Biologie

   For his leadership in the development of metabolic inhibitors by systematic chemical modification of biologically important compounds. Agents developed in this way have proven valuable in the treatment of malaria, gout, malignant diseases, disorders of the immune system, in human organ transplantation, and a variety of diseases.

3. J. Edwin Seegmiller

   Biologie

   For his elucidation of a number of inborn errors of metabolism and, in particular, for his discovery of an enzyme defect (phosphoribosyltransferase deficiency) in a neurological disease characterized by mental retardation, behavioural disturbances and over-production of uric acid.

4. Jacques Oudin

   Biologie

   In recognition of his contributions to immunochemistry through his analysis of antigen-antibody reactions in gelled media, and of his discovery and elucidation of genetic variations in the structure of immunoglobulins.

5. James L. Gowans

   Biologie

   In recognition of his contributions to a better understanding of the fate of the lymphocyte and its function in immune reactions. This work provides the experimental basis for selective suppression of immunologic mechanisms in human organ transplantations and a variety of diseases.