Prix Breakthrough · Sciences de la vie
Prix Breakthrough 2018 : lauréats
Destinataires
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Don W. Cleveland
for elucidating the molecular pathogenesis of a type of inherited ALS, including the role of glia in neurodegeneration, and for establishing antisense oligonucleotide therapy in animal models of ALS and Huntington disease.
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Joanne Chory
for discovering how plants optimize their growth, development, and cellular structure to transform sunlight into chemical energy.
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Kim Nasmyth
for elucidating the sophisticated mechanism that mediates the perilous separation of duplicated chromosomes during cell division and thereby prevents genetic diseases such as cancer.
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Peter Walter
for elucidating the unfolded protein response, a cellular quality-control system that detects disease-causing unfolded proteins and directs cells to take corrective measures.