Premio Breakthrough · Ciencias de la vida
Premio Breakthrough 2017: Ganadores
Destinatarios
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Harry F. Noller
for discovering the centrality of RNA in forming the active centers of the ribosome, the fundamental machinery of protein synthesis in all cells, thereby connecting modern biology to the origin of life and also explaining how many natural antibiotics disrupt protein synthesis.
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Huda Zoghbi
for discoveries of the genetic causes and biochemical mechanisms of spinocerebellar ataxia and Rett syndrome, findings that have provided insight into the pathogenesis of neurodegenerative and neurological diseases.
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Roel Nusse
for pioneering research on the Wnt pathway, one of the crucial intercellular signaling systems in development, cancer and stem cell biology.
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Stephen Elledge
for elucidating how eukaryotic cells sense and respond to damage in their DNA and providing insights into the development and treatment of cancer.
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Yoshinori Ohsumi
for elucidating autophagy, the recycling system that cells use to generate nutrients from their own inessential or damaged components.